In-House Laboratory Independent Research (ILIR)

Abstract

For the Uniformed Services University of the Health Sciences (USUHS), this program element supports basic medical research at the Uniformed Services University of the Health Sciences (USUHS). It facilitates the recruitment and retention of faculty; supports unique research training for military medical students and resident fellows; and allows the University’s faculty researchers to collect pilot data towards military relevant medical research projects in order to secure research funds from extramural sources (estimated $127 million annually). Approximately 130 intramural research projects are active each year, including 37 faculty start-ups. Projects are funded on a peer-reviewed, competitive basis. Results from these studies contribute to the fund of knowledge intended to enable technical approaches and investment strategies within Defense Science and Technology (S&T) programs. The ILIR program at USUHS is designed to answer fundamental questions of importance to the military medical mission of the Department of Defense in the areas of Infectious Disease, Military Operational Medicine, Combat Casualty Care, and Chemical, Biological, and Radiologic Defense. The portfolio of research projects will vary annually because this research is investigator-initiated. Examples of typical research efforts are detailed in R-2a. Infectious Disease: Immunology and molecular biology of bacterial, viral and parasitic disease threats to military operations. These threats include Bartonella bacilliformis, Clostridium difficile, E. coli and their Shiga toxins, Henipaviruses (Hendra & Nipah), Hepatitis A, Helicobacter pylori, HIV, HTLV-1, Leishmaniasis, Malaria, Neisseriae gonorrhea, Shigella spp., Streptococcus, Staphylococcus, and Typhoid fever. Military Operational Medicine: Sustainment of individual performance; mapping and managing deployment and operational stressors; cognitive enhancement; and military and medical training readiness. Combat Casualty Care: Ischemia and reperfusion injury, traumatic brain and peripheral nerve injury, neural control of pain, endotoxic shock, cryotherapy, malignant hyperthermia, inflammation, and wound healing.

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Document Details

Document Type
R2 Budgetary Justification
Publication Date
Oct 01, 2014
Source ID
0601101HP_2_0130_PB_2014
Change Summary Explanation
FY 2012: Realignment from Defense Health Program, Research, Development, Test and Evaluation (DHP RDT&E), Program Element (PE) 0601101-In-House Laboratory Independent Research (-$0.035 million) to DHP RDT&E PE 0605502-Small Business Innovation Research (SBIR) Program (+$0.035 million). FY 2013: No Change FY 2014: No Change
Service Agency Name
Defense Health Program

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Casualties
  • Combat Casualty Care
  • Department Of Defense
  • Diseases And Disorders
  • Endotoxic Shock
  • Gram-Negative Bacterial Infections
  • Infectious Diseases
  • Military Medicine
  • Military Operations
  • Molecular Biology
  • Parasitic Diseases
  • Peripheral Nervous System
  • Training
  • Vascular Diseases
  • Wound Healing

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Military Science and Technology Research and Modernization.
  • Naval Engineering and Maritime Security

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