Chemical and Biological Defense Program
Abstract
This program element (PE) resources Applied Research across the Understand, Protect, Mitigate, and Enabling Investments portfolios. Chemical and Biological Defense Program (CBDP) investments provide an integrated, layered capability to enable combating weapons of mass destruction (CWMD) missions ranging from combat operations to Department of Defense (DoD) support to domestic incident prevention and response. The Projects in this PE support applied research in the areas of physical technologies, non-traditional agent (NTA) medical and physical defense technologies, and medical technologies. These investments are a key component to sustaining the core physical and intellectual chemical and biological (CB) defense infrastructure of the Department and support the delivery of capabilities, assessments of emerging threats, and the ability to surge unique capabilities in response to a CB event. FY25 funding accelerates characterization and situational awareness of emerging biothreats and accelerates delivery of improved protection from and mitigation of biothreats, including rapid repurposing of available therapeutics and development of new vaccines. Individual Projects include: - Understand (UN2): Development of next-generation chemical and biological hazard detectors, point-of-need diagnostic devices, next-generation diagnostics systems, decision support tools, algorithms, and software. - Protect (PT2): Development of antidotes, disease surveillance medical technologies, vaccines, nerve agent pretreatments, and respiratory and ocular protection. Improvement of protection technologies and biological weapon/agent surveillance. - Mitigate (MT2): Improvement of CB defense material, including contamination avoidance and decontamination. Development of drug treatments, therapeutics, patient decontamination technologies, and individual protection advancements. - Enabling Investments (EN2): Characterization of alternate animal and microphysiological models that mimic the human response to biological and chemical agents. Development and addition of physical and intellectual infrastructure capabilities to conduct defensive classified DoD work in laboratories. Execution of a robust emerging biothreat portfolio to enable readiness for future incidents. CBDP Science and Technology (S&T) Applied Research Performers: U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC), United States Army Medical Research Institute of Infectious Diseases (USAMRIID), United States Army Medical Research Institute of Chemical Defense (USAMRICD), United States Army Natick Soldier Systems Center, Naval Research Lab (NRL), Air Force Research Lab (AFRL), and Department of Energy Laboratories such as Pacific Northwest National Laboratory (PNNL), among others. The intent is to maintain strategic partnerships with the DoD Service communities & the interagency for mission success across the enterprise through collaborative planning and programming maintaining budget assurance. Efforts under this PE will transition to or will provide risk reduction for Advanced Technology Development (PE 0603384BP), Advanced Component Development and Prototypes (PE 0603884BP), and System Development and Demonstration (PE 0604384BP) activities.
Document Details
- Document Type
- R2 Budgetary Justification
- Publication Date
- Oct 01, 2025
- Source ID
- 0602384BP_2_0400_PB_2025
- Change Summary Explanation
- Funding: FY 2023 (-$3.721 Million): Transfer of funding to support Small Business Innovative Research/Small Business Technology Transfer efforts. FY 2023 (-$0.627 Million): CBDP funding transferred to Under Secretary of Defense (Acquisition & Sustainment) high priority efforts. FY 2025 (-$6.981 Million): Applied Research adjustment to support DoD high priority efforts. Schedule: N/A Technical: N/A
- Service Agency Name
- Chemical and Biological Defense Program
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