Calcium‐sensing receptor (CaSR) as a novel target for ischemic neuroprotection
Abstract
Ischemic brain injury is the leading cause for death and long‐term disability in patients who suffer cardiac arrest and embolic stroke. Excitotoxicity and subsequent Ca2+‐overload lead to ischemic neuron death. We explore a novel mechanism concerning the role of the excitatory extracellular calcium‐sensing receptor (CaSR) in the induction of ischemic brain injury.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 03, 2014
- Source ID
- 10.1002/acn3.118
Entities
People
- Chia‐ling Tu
- Hanson Ho
- Jialing Liu
- Jong Youl Kim
- Midori A. Yenari
- Nuri Kim
- Wenhan Chang
Organizations
- American Heart Association
- National Institutes of Health
- United States Department of Defense
- United States Department of Veterans Affairs
- University of California, San Francisco