Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report

Abstract

A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 23, 2022
Source ID
10.1002/acn3.51508

Entities

People

  • Areej N. Ennasr
  • Ashraf S Gorgey
  • David X. Cifu
  • Jacob A. Goldsmith
  • Robert Trainer
  • Timothy D. Lavis
  • Tommy W. Sutor

Organizations

  • United States Department of Defense
  • Virginia Commonwealth University

Tags

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Exercise and Sports Science.
  • Neuroscience