Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment

Abstract

Changes in progranulin (GRN) expression have been hypothesized to alter risk for Alzheimer's disease (AD). We investigated the relationship between GRN expression in peripheral blood and clinical diagnosis of AD and mild cognitive impairment (MCI).

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 02, 2018
Source ID
10.1002/acn3.560

Entities

People

  • Adam L. Boxer
  • Anna M. Karydas
  • Binbin Yue
  • Bruce L. Miller
  • Daniel Nachun
  • Deepika Dokuru
  • Ginette Serrero
  • Giovanni Coppola
  • The Alzheimer’s Disease Neuroimaging Initiative*
  • Yonatan A. Cooper
  • Zhongan Yang

Organizations

  • Alzheimer's Disease Research Foundation
  • Alzheimer's Foundation of America
  • National Cancer Institute
  • National Heart, Lung, and Blood Institute
  • National Human Genome Research Institute
  • National Institute of Mental Health
  • National Institute of Neurological Disorders and Stroke
  • National Institute on Aging
  • National Institute on Drug Abuse
  • National Institutes of Health
  • United States Department of Defense
  • University of California, Los Angeles
  • University of California, San Francisco

Tags

Fields of Study

  • Psychology

Readers

  • Immunology and Pathology
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.