White matter mean diffusivity correlates with myelination in tuberous sclerosis complex
Abstract
Diffusion tensor imaging (DTI) of the white matter is a biomarker for neurological disease burden in tuberous sclerosis complex (TSC). To clarify the basis of abnormal diffusion in TSC, we correlated ex vivo high‐resolution diffusion imaging with histopathology in four tissue types: cortex, tuber, perituber, and white matter.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 23, 2019
- Source ID
- 10.1002/acn3.793
Entities
People
- Andrija Stajduhar
- Anna K. Prohl
- Benoit Scherrer
- Hart Lidov
- John J. Bushman
- Jolene M. Singh
- Joseph R. Madsen
- Jurriaan M Peters
- Lana Vasung
- Maxime Taquet
- Mustafa Şahin
- Onur Afacan
- Robbert R. Struyven
- Sanjay P Prabhu
- Simon K. Warfield
Organizations
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Harvard Medical School
- National Center for Advancing Translational Sciences
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke
- United States Department of Defense
- University of Zagreb