Reversible Bioadhesives Using Tannic Acid Primed Thermally‐Responsive Polymers
Abstract
A two‐layer approach is reported for the formation of a thermally triggered reversible adhesive, involving a thermally‐responsive polymer matrix coated on tannic acid‐pretreated substrates/tissues. Interfacial adhesion originates from strong molecular interactions of tannic acid with both the polymer matrix and the substrate/tissue. The reversibility is due to a temperature‐triggered phase transition of the polymer matrix, leading to cohesive failure. Depending on different gelation mechanisms, the polymer forms a highly cohesive gel or soft solid upon either warming or cooling, leading to a strong adhesion to the tissues at physiological temperatures. Detachment of the adhesive is triggered by a temperature‐induced compromise of cohesive strength of the polymer matrix, by the opposite gel‐to‐sol transition. This facile, low‐cost, and modular design offers a reversible adhesive platform which is useful for biomedical and industrial applications.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 20, 2019
- Source ID
- 10.1002/adfm.201907478
Entities
People
- Bin Li
- John J Whalen
- Mark S Humayun
- Mark Thompson
Organizations
- United States Army
- United States Department of Defense
- University of Southern California