Protein‐Engineered Functional Materials
Abstract
Proteins are versatile macromolecules that can perform a variety of functions. In the past three decades, they have been commonly used as building blocks to generate a range of biomaterials. Owing to their flexibility, proteins can either be used alone or in combination with other functional molecules. Advances in synthetic and chemical biology have enabled new protein fusions as well as the integration of new functional groups leading to biomaterials with emergent properties. This review discusses protein‐engineered materials from the perspectives of domain‐based designs as well as physical and chemical approaches for crosslinked materials, with special emphasis on the creation of hydrogels. Engineered proteins that organize or template metal ions, bear noncanonical amino acids (NCAAs), and their potential applications, are also reviewed.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 02, 2019
- Source ID
- 10.1002/adhm.201801374
Entities
People
- Jin K Montclare
- Priya Katyal
- Yao Wang
Organizations
- Army Research Office
- National Center for Advancing Translational Sciences
- National Institutes of Health
- National Science Foundation
- New York University