Multifunctional Biomedical Adhesives
Abstract
Currently available biomedical adhesives are mainly engineered to have one function (i.e., providing mechanical support for the repaired tissue). To improve the performance of existing bioadhesives and broaden their applications in medicine, numerous multifunctional bioadhesives are reported in the literature. These adhesives can be categorized as passive or active by design. Passive multifunctional bioadhesives contain inherent compositions and structural designs that can carry out additional functions without added external influences. These adhesives exhibit new functionalities such as antimicrobial properties, selfâhealing abilities, the ability to promote cellular ingrowth, and the ability to be reshaped. Conversely, active multifunctional bioadhesives respond to environmental changes (e.g., pH, temperature, electricity, light, and biomolecule concentration), which initiate a change in the adhesive to release encapsulated drugs or to activate or deactivate the bioadhesive for interfacial binding. This review article highlights recent advances in multifunctional bioadhesives.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 03, 2019
- Source ID
- 10.1002/adhm.201801568
Entities
People
- Bruce P Lee
- Kaylee Meyers
- Mohammad Saleh Akram Bhuiyan
- Rattapol Pinnaratip
- Rupak M. Rajachar
Organizations
- Michigan Technological University
- National Institutes of Health
- Office of Naval Research