Biomembrane‐Functionalized Micromotors: Biocompatible Active Devices for Diverse Biomedical Applications
Abstract
There has been considerable interest in developing synthetic micromotors with biofunctional, versatile, and adaptive capabilities for biomedical applications. In this perspective, cell membrane‐functionalized micromotors emerge as an attractive platform. This new class of micromotors demonstrates enhanced propulsion and compelling performance in complex biological environments, making them suitable for various in vivo applications, including drug delivery, detoxification, immune modulation, and phototherapy. This article reviews various proof‐of‐concept studies based on different micromotor designs and cell membrane coatings in these areas. The review focuses on the motor structure and performance relationship and highlights how cell membrane functionalization overcomes the obstacles faced by traditional synthetic micromotors while imparting them with unique capabilities. Overall, the cell membrane‐functionalized micromotors are expected to advance micromotor research and facilitate its translation towards practical uses.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 18, 2021
- Source ID
- 10.1002/adma.202107177
Entities
People
- Fangyu Zhang
- Joseph Wang
- Liangfang Zhang
- Nelly Askarinam
- Rodolfo Mundaca‐uribe
- Weiwei Gao
- Zhengxing Li
Organizations
- Defense Threat Reduction Agency
- National Science Foundation
- University of California, San Diego