Optically and Structurally Stabilized Plasmo‐Bio Interlinking Networks

Abstract

Visualization of dynamic interlinking networks which respond and adapt to the constantly changing environment would be highly beneficial in developing new composite materials and active/responsive materials. Here, optically and structurally stabilized plasmo‐bio interlinking networks (PBINs) free from photobleaching for high resolution, long term visualization are reported. Necessary for structural and optical stability, a new stability algorithm to comprehensively quantify stability and detect minute instability undetectable by traditional methods is introduced. Biocompatible plasmonic gold nanorods (Bio‐AuNRs) are synthesized for high resolution, long term imaging by utilizing bromide‐free alternatives to achieve CTA+ free. Systematic physical, chemical, and biological characterizations reveal the structural and optical stability of Bio‐AuNRs required for constructing PBIN. Lastly, with actin as a model of interlinking networks of the cytoskeleton, optically and structurally stable PBIN (100% CTA+ free, 97% crosslinking rate) in applications as active/responsive materials, are demonstrated.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 02, 2020
Source ID
10.1002/admi.202001370

Entities

People

  • Guangjie Cui
  • Somin Eunice Lee
  • Wei‐kuan Lin
  • Xingchen Ye
  • Xintao Zhao
  • Yi Wang
  • Younggeun Park
  • Yunbo Liu
  • Zachary Burns
  • Zhijia Zhang

Organizations

  • Air Force Office of Scientific Research
  • Indiana University
  • National Science Foundation
  • University of Michigan

Tags

Readers

  • Nanocomposite Materials Science
  • Neural Network Machine Learning.
  • Systems Analysis and Design