3D Printed Organ Models with Physical Properties of Tissue and Integrated Sensors

Abstract

The design and development of novel methodologies and customized materials to fabricate patient‐specific 3D printed organ models with integrated sensing capabilities can yield advances in smart surgical aids for preoperative planning and rehearsal. Here, 3D printed prostate models are demonstrated with physical properties of tissue and integrated soft electronic sensors using custom‐formulated polymeric inks. The models show high quantitative fidelity in static and dynamic mechanical properties, optical characteristics, and anatomical geometries to patient tissues and organs. The models offer tissue‐mimicking tactile sensation and behavior and thus can be used for the prediction of organ physical behavior under deformation. The prediction results show good agreement with values obtained from simulations. The models also allow the application of surgical and diagnostic tools to their surface and inner channels. Finally, via the conformal integration of 3D printed soft electronic sensors, pressure applied to the models with surgical tools can be quantitatively measured.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 06, 2017
Source ID
10.1002/admt.201700235

Entities

People

  • Badrinath R. Konety
  • Brenda M. Ogle
  • Chih‐chang Chu
  • Daniel A. Saltzman
  • Didarul B. Bhuiyan
  • Fanben Meng
  • Ghazaleh Haghiashtiani
  • Kaiyan Qiu
  • Michael McAlpine
  • Mingyu He
  • Paari Murugan
  • Robert Sweet
  • Ruitao Su
  • Shuang‐zhuang Guo
  • Sung Hyun Park
  • Zhijie Zhu
  • Zichen Zhao

Organizations

  • Army Research Office
  • Cornell University
  • National Institutes of Health
  • University of Minnesota
  • University of Washington

Tags

Readers

  • Computational Modeling and Simulation
  • Manufacturing Engineering.
  • Trauma or Military Medicine

Technology Areas

  • Microelectronics