APOE interacts with tau PET to influence memory independently of amyloid PET in older adults without dementia
Abstract
Apolipoprotein E (APOE) interacts with Alzheimer's disease pathology to promote disease progression. We investigated the moderating effect of APOE on independent associations of amyloid and tau positron emission tomography (PET) with cognition.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 04, 2020
- Source ID
- 10.1002/alz.12173
Entities
People
- Adam M. Brickman
- Alexandra J. Weigand
- For The Alzheimer’s Disease Neuroimaging Initiative*
- Graham M.l. Eglit
- Katherine J. Bangen
- Kelsey R Thomas
- Lisa Delano‐wood
- Mark W. Bondi
- Paul E. Gilbert
Organizations
- Alzheimer's Disease Neuroimaging Initiative
- Columbia University Vagelos College of Physicians and Surgeons
- National Institute of Biomedical Imaging and Bioengineering
- National Institute on Aging
- National Science Foundation
- San Diego State University
- United States Department of Defense