Spinal cord gray matter atrophy correlates with multiple sclerosis disability
Abstract
In multiple sclerosis (MS), cerebral gray matter (GM) atrophy correlates more strongly than white matter (WM) atrophy with disability. The corresponding relationships in the spinal cord (SC) are unknown due to technical limitations in assessing SC GM atrophy. Using phase‐sensitive inversion recovery (PSIR) magnetic resonance imaging, we determined the association of the SC GM and SC WM areas with MS disability and disease type.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 21, 2014
- Source ID
- 10.1002/ana.24241
Entities
People
- Alyssa H. Zhu
- Ari J. Green
- Bruce A C Cree
- Carolyn Bevan
- Douglas S. Goodin
- Eduardo Caverzasi
- Emmanuelle Waubant
- H.‐christian Von Büdingen
- Iryna V. Lobach
- Jeffrey M. Gelfand
- Kesshi M Jordan
- Monica Bucci
- Nico Papinutto
- Regina Schlaeger
- Roland G. Henry
- Stephen L. Hauser
- Valentina Panara
- William A. Stern
Organizations
- Conrad N. Hilton Foundation
- Howard Hughes Medical Institute
- National Institutes of Health
- National Multiple Sclerosis Society
- Race to Erase MS
- United States Department of Defense
- University of Basel
- University of California, San Francisco