Brain Connectivity Predicts Chronic Pain in Acute Mild Traumatic Brain Injury
Abstract
Previous studies have established the role of the cortico‐mesolimbic and descending pain modulation systems in chronic pain prediction. Mild traumatic brain injury (mTBI) is an acute pain model where chronic pain is prevalent and complicated for prediction. In this study, we set out to study whether functional connectivity (FC) of the nucleus accumbens (NAc) and the periaqueductal gray matter (PAG) is predictive of pain chronification in early‐acute mTBI.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 09, 2022
- Source ID
- 10.1002/ana.26463
Entities
People
- Amir Lawen
- Apkar Vania Apkarian
- Chen Buxbaum
- David Yarnitsky
- Itamar Kahn
- Michele Sterling
- Noam Bosak
- Noam Saadon‐grosman
- Paulo Branco
- Pora Kuperman
- Rabab Zubeidat
- Rafi Hadad
- Ruth Manor Cohen
- Shiri Fadel
- Yelena Granovsky
Organizations
- Hebrew University of Jerusalem
- Northwestern University
- Technion – Israel Institute of Technology
- United States Department of Defense
- University of Queensland