Relative Contributions of Mixed Pathologies to Cognitive and Functional Symptoms in Brain Donors Exposed to Repetitive Head Impacts
Abstract
Exposure to repetitive head impacts (RHI) is associated with later‐life cognitive symptoms and neuropathologies, including chronic traumatic encephalopathy (CTE). Cognitive decline in community cohorts is often due to multiple pathologies; however, the frequency and contributions of these pathologies to cognitive impairment in people exposed to RHI are unknown. Here, we examined the relative contributions of 13 neuropathologies to cognitive symptoms and dementia in RHI‐exposed brain donors.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 21, 2023
- Source ID
- 10.1002/ana.26823
Entities
People
- Aliyah Olaniyan
- Ann C. Mckee
- Arsal Shah
- Bertrand Huber
- Bobak Abdolmohammadi
- Brett Martin
- Brigid Dwyer
- Christopher J. Nowinski
- Daniel H Daneshvar
- Douglas I. Katz
- Eukyung Yhang
- Evan Nair
- Jesse Mez
- Joseph N. Palmisano
- Julie A. Schneider
- Madeline Uretsky
- Michael L Alosco
- Nicole Saltiel
- Patricia A. Boyle
- Raymond Nicks
- Robert A. Stern
- Robert C. Cantu
- Talia Menzin
- Thor D Stein
- Victor E. Alvarez
- Yorghos Tripodis
- Zach Baucom
Organizations
- Boston University
- Emerson Hospital
- National Center for Post Traumatic Stress Disorder
- National Institute of Neurological Disorders and Stroke
- National Institute on Aging
- Rush University
- United States Department of Defense
- United States Department of Veterans Affairs
- VA Boston Healthcare System