Self‐Assembly of Wireframe DNA Nanostructures from Junction Motifs
Abstract
Wireframe frameworks have been investigated for the construction of complex nanostructures from a scaffolded DNA origami approach; however, a similar framework is yet to be fully explored in a scaffold‐free “LEGO” approach. Herein, we describe a general design scheme to construct wireframe DNA nanostructures entirely from short synthetic strands. A typical edge of the resulting structures in this study is composed of two parallel duplexes with crossovers on both ends, and three, four, or five edges radiate out from a certain vertex. By using such a self‐assembly scheme, we produced planar lattices and polyhedral objects.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 24, 2019
- Source ID
- 10.1002/ange.201906408
Entities
People
- Bryan Wei
- Chengde Mao
- Donglei Yang
- Kai Huang
- Silian Chen
- Ye Xiang
- Yongli Mi
- Zhenyu Tan
Organizations
- Hong Kong University of Science and Technology
- National Natural Science Foundation of China
- Office of Naval Research
- Peking University
- Purdue University
- Shanghai Jiao Tong University
- Tongji University
- Tsinghua University
- University of Michigan