Parahydrogen‐Induced Radio Amplification by Stimulated Emission of Radiation
Abstract
Radio amplification by stimulated emission of radiation (RASER) was recently discovered in a low‐field NMR spectrometer incorporating a highly specialized radio‐frequency resonator, where a high degree of proton‐spin polarization was achieved by reversible parahydrogen exchange. RASER activity, which results from the coherent coupling between the nuclear spins and the inductive detector, can overcome the limits of frequency resolution in NMR. Here we show that this phenomenon is not limited to low magnetic fields or the use of resonators with high‐quality factors. We use a commercial bench‐top 1.4 T NMR spectrometer in conjunction with pairwise parahydrogen addition producing proton‐hyperpolarized molecules in the Earth's magnetic field (ALTADENA condition) or in a high magnetic field (PASADENA condition) to induce RASER without any radio‐frequency excitation pulses. The results demonstrate that RASER activity can be observed on virtually any NMR spectrometer and measures most of the important NMR parameters with high precision.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 24, 2020
- Source ID
- 10.1002/ange.201916597
Entities
People
- Baptiste Joalland
- Eduard Y. Chekmenev
- Nuwandi M Ariyasingha
- Stephan Appelt
- Sören Lehmkuhl
- Thomas Theis
Organizations
- Congressionally Directed Medical Research Programs
- Edward Mallinckrodt Jr. Foundation
- National Cancer Institute
- National Institute of Biomedical Imaging and Bioengineering
- National Science Foundation Directorate for Mathematical & Physical Sciences
- North Carolina Biotechnology Center
- North Carolina State University
- RWTH Aachen University
- Russian Academy of Sciences
- Yusuf Hamied Department of Chemistry