Anisotropic Synthetic Allomelanin Materials via Solid‐State Polymerization of Self‐Assembled 1,8‐Dihydroxynaphthalene Dimers

Abstract

Melanosomes in nature have diverse morphologies, including spheres, rods, and platelets. By contrast, shapes of synthetic melanins have been almost entirely limited to spherical nanoparticles with few exceptions produced by complex templated synthetic methods. Here, we report a non‐templated method to access synthetic melanins with a variety of architectures including spheres, sheets, and platelets. Three 1,8‐dihydroxynaphthalene dimers (4‐4′, 2‐4′ and 2‐2′) were used as self‐assembling synthons. These dimers pack to form well‐defined structures of varying morphologies depending on the isomer. Specifically, distinctive ellipsoidal platelets can be obtained using 4‐4′ dimers. Solid‐state polymerization of the preorganized dimers generates polymeric synthetic melanins while maintaining the initial particle morphologies. This work provides a new route to anisotropic synthetic melanins, where the building blocks are preorganized into specific shapes, followed by solid‐state polymerization.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 24, 2021
Source ID
10.1002/ange.202103447

Entities

People

  • Arthi Jayaraman
  • Christopher J. Forman
  • Christos D Malliakas
  • Hao Sun
  • Julia Oktawiec
  • Liliana D'Alba
  • Matthew D. Shawkey
  • Matthew P. Thompson
  • Naneki C McCallum
  • Nathan C. Gianneschi
  • Omar Farha
  • Utkarsh Kapoor
  • Wei Cao
  • Xinyi Gong
  • Xuhao Zhou
  • Ziying Hu

Organizations

  • Air Force Office of Scientific Research
  • Ghent University
  • Northwestern University
  • University of Delaware

Tags

Fields of Study

  • Chemistry

Readers

  • Nanoscale Plasmonic Nanotechnology
  • Polymer Science and Technology

Technology Areas

  • Biotechnology