Effectiveness of the soluble form of the interleukin‐1 receptor accessory protein as an inhibitor of interleukin‐1 in collagen‐induced arthritis

Abstract

To investigate whether the soluble form of interleukin‐1 (IL‐1) receptor accessory protein (sIL‐1RAcP), whose physiologic function remains to be established, can serve as a specific inhibitor of IL‐1 signaling in vitro, and to evaluate its applicability in collagen‐induced arthritis (CIA).

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 01, 2003
Source ID
10.1002/art.11234

Entities

People

  • David T. Curiel
  • F. A. J. Van De Loo
  • I. P. Dmitriev
  • L. A. B. Joosten
  • M. B. Bennink
  • M. U. Martin
  • O. J. Arntz
  • R. L. Smeets
  • W. A. Loesberg
  • W. B. Van Den Berg

Organizations

  • National Institutes of Health
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Industrial Economics