Suppression of Inflammatory Arthritis by Human Gut‐Derived Prevotella histicola in Humanized Mice
Abstract
The gut microbiome regulates host immune homeostasis. Rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This study was undertaken to test the ability of a human gut‐derived commensal to modulate immune response and treat arthritis in a humanized mouse model.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 28, 2016
- Source ID
- 10.1002/art.39785
Entities
People
- Abhinav Lamba
- Ashutosh Mangalam
- David H. Luckey
- Eric V. Marietta
- Harvinder S. Luthra
- Joseph A. Murray
- Patricio R. Jeraldo
- Robin Patel
- Veena Taneja
Organizations
- Congressionally Directed Medical Research Programs
- Mayo Clinic