Feature selective temporal prediction of Alzheimer's disease progression using hippocampus surface morphometry

Abstract

Prediction of Alzheimer's disease (AD) progression based on baseline measures allows us to understand disease progression and has implications in decisions concerning treatment strategy. To this end, we combine a predictive multi‐task machine learning method (cFSGL) with a novel MR‐based multivariate morphometric surface map of the hippocampus (mTBM) to predict future cognitive scores of patients.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 09, 2017
Source ID
10.1002/brb3.733

Entities

People

  • Jiayu Zhou
  • Jie Shi
  • Jieping Ye
  • Natasha Leporé
  • Niharika Gajawelli
  • Sinchai Tsao
  • Yalin Wang

Organizations

  • Alzheimer's Disease Neuroimaging Initiative
  • Arizona State University
  • Canadian Institutes of Health Research
  • Michigan State University
  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • United States Department of Defense
  • University of Michigan
  • University of Southern California

Tags

Readers

  • Neural Network Machine Learning.
  • Neuroscience
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.

Technology Areas

  • AI & ML
  • AI & ML - Bayesian Inference
  • AI & ML - Neural Networks