Defining fallopian tube‐derived miRNA cancer signatures
Abstract
MicroRNAs have recently emerged as promising circulating biomarkers in diverse cancer types, including ovarian cancer. We utilized conditional, doxycycline‐induced fallopian tube (FT)‐derived cancer models to identify changes in miRNA expression in tumors and plasma, and further validated the murine findings in high‐grade ovarian cancer patient samples.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 10, 2019
- Source ID
- 10.1002/cam4.2416
Entities
People
- Anand Bradley
- Anders Ohman
- Daniela M. Dinulescu
- Deepinder Randhawa
- Kevin M. Elias
- Niraj Yadav
- Selam B. Dejene
- Sunita R Setlur
- Wei Du
Organizations
- Brigham and Women's Hospital
- Harvard Medical School
- Harvard University
- Honorable Tina Brozman Foundation
- Minnesota Ovarian Cancer Alliance
- National Institutes of Health
- Ovarian Cancer Research Alliance
- United States Department of Defense