Automated analysis of computerized morphological features of cell clusters associated with malignancy on bile duct brushing whole slide images

Abstract

Bile duct brush specimens are difficult to interpret as they often present inflammatory and reactive backgrounds due to the local effects of stricture, atypical reactive changes, or previously installed stents, and often have low to intermediate cellularity. As a result, diagnosis of biliary adenocarcinomas is challenging and often results in large interobserver variability and low sensitivity

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 24, 2022
Source ID
10.1002/cam4.5365

Entities

People

  • Anant Madabhushi
  • Aparna Harbhajanka
  • Behtash G. Nezami
  • Claire W. Michael
  • Kaustav Bera
  • Patrick Leo
  • Shayan Monabbati

Organizations

  • Case Western Reserve University
  • Clinical and Translational Science Collaborative of Northern Ohio
  • National Cancer Institute
  • National Center for Research Resources
  • National Institute of Biomedical Imaging and Bioengineering

Tags

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.