Impact of genomic testing on urologists' treatment preference in favorable risk prostate cancer: A randomized trial

Abstract

The Oncotype Dx Genomic Prostate Score (GPS) is a 17‐gene relative expression assay that predicts adverse pathology at prostatectomy. We conducted a novel randomized controlled trial to assess the impact of GPS on urologist's treatment preference for favorable risk prostate cancer (PCa): active surveillance versus active treatment (i.e., prostatectomy/radiation). This is a secondary endpoint from the ENACT trial which recruited from three Chicago hospitals from 2016 to 2019.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 01, 2023
Source ID
10.1002/cam4.6615

Entities

People

  • Adam B Murphy
  • Andre Kajdacsy‐balla
  • Carol E. Ferrans
  • Cordero Mccall
  • Courtney M.P. Hollowell
  • Daniel Moreira
  • Heidy Wang
  • Karen Ferrer
  • Li Ping
  • Lisa K. Sharp
  • Marin Sekosan
  • Marlene Gallegos
  • Michael Abern
  • Norma Marshall
  • Patricia Vidal
  • Peter H Gann
  • Roohollah Sharifi
  • Samuel Carbunaru
  • Shoujin Wu
  • Zequn Sun

Organizations

  • Duke University
  • Jesse Brown VA Medical Center
  • John H. Stroger, Jr. Hospital of Cook County
  • Medical College of Wisconsin
  • Northwestern University
  • United States Department of Defense
  • University of Illinois at Chicago

Tags

Fields of Study

  • Biology
  • Medicine

Readers

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Technology Areas

  • Space