A case series of a mother and two daughters with a GLI2 gene deletion demonstrating variable expressivity and incomplete penetrance

Abstract

This case series and review of the literature support that patients with pathogenic variants of the GLI2 gene demonstrate an autosomal dominant inheritance pattern, variable expressivity, and incomplete penetrance.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 30, 2020
Source ID
10.1002/ccr3.3085

Entities

People

  • Cameron Elward
  • Janet Berg
  • John M. Oberlin
  • Luis Rohena

Organizations

  • San Antonio Military Medical Center

Tags

Readers

  • Molecular and genetic basis of cancer.