Enzymatic Bioelectrocatalysis for Enzymology Applications

Abstract

Enzymatic biosensors are commonly used to evaluate the concentration of individual analytes in samples (e. g., glucose in blood, lactate in sweat, etc.), where the working electrode utilizes an enzyme (a “bioelectrode”) as the chemically selective agent for electrochemical analyses. However, those same enzymatic bioelectrodes can be used for the analytical characterization of enzymes as a new biophysical characterization tool for enzymologists. This Minireview will detail recent work focused on utilizing enzymatic bioelectrocataysis for enzymology applications. Specifically, it will talk about the use of enzymatic bioelectrodes for studying kinetics, inhibition, transport, and thermodynamics. It will also compare and contrast electrochemical techniques with spectrophotometric techniques for enzymology.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 06, 2020
Source ID
10.1002/celc.202000239

Entities

People

  • Matthew J. Kummer
  • Shelley D. Minteer

Organizations

  • Air Force Office of Scientific Research
  • University of Utah

Tags

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Electrochemical Surface Science
  • Molecular Genetics

Technology Areas

  • Biotechnology