Detoxification of Chemical Warfare Agents Using a Zr6‐Based Metal–Organic Framework/Polymer Mixture

Abstract

Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium‐based metal–organic frameworks (Zr6‐MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant, dimethyl 4‐nitrophenylphosphate (DMNP), in buffered solutions. A hurdle to using MOFs for this application is the current need for a buffer solution. Here the destruction of the simulant DMNP, as well as the chemical warfare agents (GD and VX) through hydrolysis using a MOF catalyst mixed with a non‐volatile, water‐insoluble, heterogeneous buffer is reported. The hydrolysis of the simulant and nerve agents in the presence of the heterogeneous buffer was fast and effective.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 08, 2016
Source ID
10.1002/chem.201603976

Entities

People

  • Ashlee Howarth
  • Emmanuel Proussaloglou
  • Gregory W. Peterson
  • Jared B DeCoste
  • Joseph T. Hupp
  • Morgan G. Hall
  • Omar Farha
  • Su‐young Moon

Organizations

  • Edgewood Chemical Biological Center
  • King Abdulaziz University
  • National Science Foundation
  • Northwestern University

Tags

Readers

  • Analytical Chemistry
  • Nanocomposite Materials Science
  • Neurotoxicology