BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
Abstract
It is believed that BRCA1 and BRCA2 germline mutations account for the majority of hereditary ovarian carcinomas; however, to the authors' knowledge, there are scant data on the prevalence and spectrum of mutations, genotype/phenotype correlations, tumor histology, and family history characteristics. To address this gap, the authors conducted a population‐based study of 232 incident epithelial ovarian carcinomas in the Tampa Bay area.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 14, 2005
- Source ID
- 10.1002/cncr.21536
Entities
People
- Alan B Cantor
- George Wilbanks
- Hector Arango
- James Fiorica
- James Lapolla
- Jeffrey P Krischer
- Jenny Permuth‐wey
- Judith A. Betts
- Katie Wakeley
- Martin A. Martino
- Mitchell Hoffman
- Rebecca Sutphen
- Santo Nicosia
- Tuya Pal
Organizations
- United States Department of Defense