Circulating vitamin D, vitamin D–related genetic variation, and risk of fatal prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
Abstract
Evidence from experimental animal and cell line studies supports a beneficial role for vitamin D in prostate cancer (PCa). Although the results from human studies have been mainly null for overall PCa risk, there may be a benefit for survival. This study assessed the associations of circulating 25‐hydroxyvitamin D (25(OH)D) and common variations in key vitamin D–related genes with fatal PCa.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 02, 2015
- Source ID
- 10.1002/cncr.29320
Entities
People
- Alison M. Mondul
- Demetrius Albanes
- Edward L. Giovannucci
- For The Breast And Prostate Cancer Cohort Consortium Group
- Irene M Shui
- Konstantinos K. Tsilidis
- Lorelei A. Mucci
- Peter Kraft
- Ruth Travis
- Sara Lindström
- Travis Gerke
Organizations
- Brigham and Women's Hospital
- Fred Hutchinson Cancer Center
- Harvard T.H. Chan School of Public Health
- National Cancer Institute
- National Institutes of Health
- United States Department of Defense
- University of Florida
- University of Ioannina
- University of Michigan
- University of Oxford