Dietary intake of fish, polyunsaturated fatty acids, and survival after breast cancer: A population‐based follow‐up study on Long Island, New York

Abstract

In laboratory experiments, ω‐3 polyunsaturated fatty acids (PUFAs) have been found to reduce inflammatory eicosanoids resulting from ω‐6 PUFA metabolism via competitive inhibition, and the ω‐3‐induced cytotoxic environment increases apoptosis and reduces cell growth in breast cancer cells. To the authors' knowledge, epidemiologic investigations regarding whether dietary ω‐3 PUFA intake benefits survival after breast cancer are limited and inconsistent.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 24, 2015
Source ID
10.1002/cncr.29329

Entities

People

  • Alfred I. Neugut
  • Andrew F. Olshan
  • Habibul Ahsan
  • Jing Shen
  • Jiyoung Ahn
  • Ka He
  • Marilie D. Gammon
  • Mary Beth Terry
  • Nikhil K. Khankari
  • Patrick T. Bradshaw
  • Regina M. Santella
  • Susan E Steck
  • Susan L. Teitelbaum
  • Yu Chen

Organizations

  • Columbia University
  • Icahn School of Medicine at Mount Sinai
  • Indiana University
  • National Institutes of Health
  • New York University
  • United States Army
  • University of Chicago
  • University of South Carolina

Tags

Readers

  • Breast cancer cell signaling and growth regulation.
  • Prostate Cancer Biology.