Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer
Abstract
Obese men are at higher risk of advanced prostate cancer and cancer‐specific mortality; however, the biology underlying this association remains unclear. This study examined gene expression profiles of prostate tissue to identify biological processes differentially expressed by obesity status and lethal prostate cancer.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 12, 2017
- Source ID
- 10.1002/cncr.30831
Entities
People
- David Labbé
- Edward L. Giovannucci
- Ericka M Ebot
- Giorgia Zadra
- Irene M Shui
- Jennifer A. Sinnott
- Jennifer R Stark
- Kathryn M. Wilson
- Lorelei A. Mucci
- Massimo Loda
- Matthew G Vander Heiden
- Myles A. Brown
- Philip W. Kantoff
- Rachel S Kelly
- Stephen P. Finn
- Svitlana Tyekucheva
- Travis Gerke
Organizations
- Boston University
- Canadian Institutes of Health Research
- Cancer Research Society
- Dana–Farber Cancer Institute
- H. Lee Moffitt Cancer Center & Research Institute
- Harvard Medical School
- Harvard University
- Howard Hughes Medical Institute
- Irish Cancer Society
- Massachusetts Institute of Technology
- Memorial Sloan Kettering Cancer Center
- National Institutes of Health
- Ohio State University
- Prostate Cancer Foundation
- Stand Up to Cancer
- Trinity College Dublin
- United States Department of Defense
- World Cancer Research Fund UK