Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences
Abstract
Although cell lines are an essential resource for studying cancer biology, many are of unknown ancestral origin, and their use may not be optimal for evaluating the biology of all patient populations.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 13, 2019
- Source ID
- 10.1002/cncr.32020
Entities
People
- George L. Maxwell
- Julie C Dunning Hotopp
- Michael D Kessler
- Nicholas W Bateman
- Thomas P Conrads
- Timothy D. O'connor
Organizations
- Congressionally Directed Medical Research Programs
- Inova Health System
- National Cancer Institute Egypt
- National Heart, Lung, and Blood Institute
- National Human Genome Research Institute
- National Institutes of Health
- Uniformed Services University of the Health Sciences
- University of Maryland