Tumor dormancy in bone
Abstract
Bone marrow is a common site of metastasis for a number of tumor types, including breast, prostate, and lung cancer, but the mechanisms controlling tumor dormancy in bone are poorly understood. In breast cancer, while advances in drug development, screening practices, and surgical techniques have dramatically improved survival rates in recent decades, metastatic recurrence in the bone remains common and can develop years or decades after elimination of the primary tumor.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 29, 2019
- Source ID
- 10.1002/cnr2.1156
Entities
People
- Rachelle Whitney Johnson
- Tolu Omokehinde
- Vera Mayhew
Organizations
- Congressionally Directed Medical Research Programs
- Howard Hughes Medical Institute
- National Cancer Institute
- National Institutes of Health
- Vanderbilt University