Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb
Abstract
Despite improved surgical approaches for chronic limb‐threatening ischemia (CLTI), amputation rates remain high and contributing tissue‐level factors remain unknown. The purpose of this study was twofold: (1) to identify differences between the healthy adult and CLTI limb muscle proteome, and (2) to identify differences in the limb muscle proteome of CLTI patients prior to surgical intervention or at the time of amputation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2022
- Source ID
- 10.1002/ctm2.658
Entities
People
- Dean J. Yamaguchi
- Joseph M. Mcclung
- Kelsey H. Fisher‐wellman
- Kerri A. O'malley
- Kyoungrae Kim
- Reema Karnekar
- Salvatore T. Scali
- Scott A. Berceli
- Terence E Ryan
- Thomas D. Green
- Trace Thome
- Zachary R. Salyers
Organizations
- American Heart Association
- East Carolina University
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute on Aging
- United States Department of Defense
- University of Florida