Deep learning improves utility of tau PET in the study of Alzheimer's disease

Abstract

Positron emission tomography (PET) imaging targeting neurofibrillary tau tangles is increasingly used in the study of Alzheimer's disease (AD), but its utility may be limited by conventional quantitative or qualitative evaluation techniques in earlier disease states. Convolutional neural networks (CNNs) are effective in learning spatial patterns for image classification.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2021
Source ID
10.1002/dad2.12264

Entities

People

  • Adam M. Brickman
  • Aubrey Johnson
  • David Park
  • Devangere P. Devanand
  • For The Alzheimer’s Disease Neuroimaging Initiative*
  • Frank A. Provenzano
  • James Zou
  • Jeanelle France
  • José A. Luchsinger
  • Michelle Pardo
  • William C. Kreisl
  • Xinyang Feng
  • Zeljko Tomljanovic

Organizations

  • Columbia University
  • National Institutes of Health

Tags

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Neural Network Machine Learning.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.

Technology Areas

  • AI & ML
  • AI & ML - Neural Networks