Immunity gene IFITM3 variant: Relation to cognition and Alzheimer's disease pathology

Abstract

We investigated single‐nucleotide polymorphisms (SNPs) in IFITM3, an innate immunity gene and modulator of amyloid beta in Alzheimer's disease (AD), for association with cognition and AD biomarkers.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2022
Source ID
10.1002/dad2.12317

Entities

People

  • Andrew J. Saykin
  • Angela Hodges
  • For The Addneuromed Consortium And The Alzheimer's Disease Neuroimaging Initiative
  • Jae-Won Jang
  • Jung‐min Pyun
  • Kwangsik Nho
  • Paula J. Bice
  • Sangyun Kim
  • Young Ho Park

Organizations

  • Indiana University
  • Indiana University School of Medicine
  • Kangwon National University
  • King's College London
  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • Seoul National University
  • Soonchunhyang University
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular and genetic basis of cancer.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.