Cross‐talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification
Abstract
Progressive maturation of growth plate chondrocytes drives long bone growth during endochondral ossification. Signals from the epidermal growth factor receptor (EGFR), and from bone morphogenetic protein‐2 (BMP2), are required for normal chondrocyte maturation. Here, we investigated cross‐talk between EGFR and BMP2 signals in developing and adult growth plates.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 27, 2021
- Source ID
- 10.1002/dvdy.438
Entities
People
- Caroline N. Dealy
- David W. Threadgill
- John B. Lees‐shepard
- Kaitlyn Flint
- Kelsey Richard
- Melanie Fisher
- Michelle Antony
- Minoru Omi
- Nita J. Maihle
- Po Jung Chen
- Sumit Yadav
Organizations
- United States Department of Defense
- University of Connecticut
- University of Mississippi