Perfluoropyridine as an Efficient, Tunable Scaffold for Bis(pyrazol‐1‐yl)pyridine Copper Complexes
Abstract
This report details the syntheses of five new 2,6‐bis(pyrazol‐1‐yl)pyridine ligands carried out by a unique strategy of utilizing pentafluoropyridine for the pyridine core. Formation of each ligand is accomplished under mild conditions utilizing carbonate bases. Each ligand reacts readily with copper(II) triflate to form the corresponding salt in high yield. Ligands and complexes were characterized by a combination of multi‐nuclear NMR, FTIR, UV/Vis, and single‐crystal X‐ray diffraction. Copper(II) triflate complexes demonstrating additional coordination modes of this multi‐pyrazole ligand system were also obtained. Despite the electron withdrawing nature of fluorine, the coordination parameters of the new complexes are comparable to previous pyrazole‐based complexes. This synthetic methodology provides efficient entry to a previously difficult to access ligand system.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 08, 2020
- Source ID
- 10.1002/ejic.202000150
Entities
People
- Andrew J Peloquin
- Colin D McMillen
- Matthew Houck
- Scott T Iacono
- William T. Pennington
Organizations
- Air Force Institute of Technology
- Air Force Office of Scientific Research
- Clemson University
- United States Air Force Academy