A companion to the preclinical common data elements and case report forms for rodent EEG studies. A report of the TASK3 EEG Working Group of the ILAE/AES Joint Translational Task Force

Abstract

Electroencephalography (EEG) is commonly used in epilepsy and neuroscience research to study brain activity. The principles of EEG recording such as signal acquisition, digitization, and conditioning share similarities between animal and clinical EEG systems. In contrast, preclinical EEG studies demonstrate more variability and diversity than clinical studies in the types and locations of EEG electrodes, methods of data analysis, and scoring of EEG patterns and associated behaviors. The TASK3 EEG working group of the International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force has developed a set of preclinical common data elements (CDEs) and case report forms (CRFs) for recording, analysis, and scoring of animal EEG studies. This companion document accompanies the first set of proposed preclinical EEG CRFs and is intended to clarify the CDEs included in these worksheets. We provide 7 CRF and accompanying CDE modules for use by the research community, covering video acquisition, electrode information, experimental scheduling, and scoring of EEG activity. For ease of use, all data elements and input ranges are defined in supporting Excel charts (Appendix S1).

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 24, 2018
Source ID
10.1002/epi4.12260

Entities

People

  • Aristea S Galanopoulou
  • Filippo S. Giorgi
  • Jason T. Moyer
  • John Jefferys
  • Joost Wagenaar
  • Lauren C. Harte‐hargrove
  • Petr Fabera
  • Ryosuke Hanaya
  • Tomonori Ono

Organizations

  • Albert Einstein College of Medicine
  • Charles University
  • International League Against Epilepsy
  • Kagoshima University
  • National Institute of Neurological Disorders and Stroke
  • United States Department of Defense
  • University of Oxford
  • University of Pennsylvania
  • University of Pisa

Tags

Fields of Study

  • Medicine

Readers

  • Canadian European Scientific Immigration and Epilepsy Clearance Studies
  • Clinical Trial Research.
  • Computer Science.