Global resting‐state functional connectivity of neural oscillations in tinnitus with and without hearing loss
Abstract
This study examined global resting‐state functional connectivity of neural oscillations in individuals with chronic tinnitus and normal and impaired hearing. We tested the hypothesis that distinct neural oscillatory networks are engaged in tinnitus with and without hearing loss. In both tinnitus groups, with and without hearing loss, we identified multiple frequency band‐dependent regions of increased and decreased global functional connectivity. We also found that the auditory domain of tinnitus severity, assayed by the Tinnitus Functional Index, was associated with global functional connectivity in both auditory and nonauditory regions. These findings provide candidate biomarkers to target and monitor treatments for tinnitus with and without hearing loss.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 03, 2020
- Source ID
- 10.1002/hbm.24981
Entities
People
- Anne Findlay
- Carly Demopoulos
- Caroline Racine‐belkoura
- Coleman Garrett
- Danielle Mizuiri
- Jennifer Henderson‐sabes
- Kamalini G Ranasinghe
- Leighton B. Hinkley
- Srikantan S. Nagarajan
- Steven W. Cheung
- Susanne Honma
- Xuan Duong
Organizations
- National Institute on Deafness and Other Communication Disorders
- Palo Alto University
- United States Department of Defense
- University of California, San Francisco