Surgical molecular navigation with ratiometric activatable cell penetrating peptide for intraoperative identification and resection of small salivary gland cancers
Abstract
We evaluated the use of intraoperative fluorescence guidance by enzymatically cleavable ratiometric activatable cell‐penetrating peptide (RACPPPLGC(Me)AG) containing Cy5 as a fluorescent donor and Cy7 as a fluorescent acceptor for salivary gland cancer surgery in a mouse model.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 22, 2015
- Source ID
- 10.1002/hed.23946
Entities
People
- Elamprakash N. Savariar
- Julio A. Diaz–perez
- Karen Messer
- Minya Pu
- Quyen T. Nguyen
- Roger Y. Tsien
- Timon Hussain
Organizations
- Burroughs Wellcome Fund
- Foundation for the National Institutes of Health
- United States Department of Defense
- University of California, San Diego