Menstrual and reproductive characteristics and breast cancer risk by hormone receptor status and ethnicity: The Breast Cancer Etiology in Minorities study
Abstract
We pooled multiethnic data from four population‐based studies and examined associations of menstrual and reproductive characteristics with breast cancer (BC) risk by tumor hormone receptor (HR) status [defined by estrogen receptor (ER) and progesterone receptor (PR)]. We estimated odds ratios and 95% confidence intervals using multivariable logistic regression, stratified by age (vs. 1 FTP) was increased fourfold in women who never breast‐fed, but not in those with a breast‐feeding history, suggesting that breast‐feeding may mitigate the adverse effect of higher parity in younger African American women. Further work needs to evaluate why menstrual and reproductive risk factors vary in importance according to age and ethnicity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 29, 2020
- Source ID
- 10.1002/ijc.32923
Entities
People
- Amanda I. Phipps
- Anna H. Wu
- Esther M. John
- Jocelyn Koo
- Kathy B. Baumgartner
- Lisa M. Hines
- Martha L Slattery
- Sue A. Ingles
Organizations
- California Breast Cancer Research Program
- Fred Hutchinson Cancer Center
- National Cancer Institute
- Stanford University
- United States Army Medical Research and Development Command
- University of Colorado, at Colorado Springs
- University of Louisville
- University of Southern California
- University of Utah
- University of Washington