Hormesis: Transforming disciplines that rely on the dose response
Abstract
This article tells the story of hormesis from its conceptual and experimental origins, its dismissal by the scientific and medical communities in the first half of the 20th century, and its rediscovery over the past several decades to be a fundamental evolutionary adaptive strategy. The upregulation of hormetic adaptive mechanisms has the capacity to decelerate the onset and reduce the severity of a broad spectrum of common age‐related health, behavioral, and performance decrements and debilitating diseases, thereby significantly enhancing the human health span. Incorporation of hormetic‐based lifestyle options within the human population would have profoundly positive impacts on the public health, significantly reducing health care costs.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 23, 2021
- Source ID
- 10.1002/iub.2529
Entities
People
- Edward Calabrese
- Evgenios Agathokleous
Organizations
- Air Force Office of Scientific Research
- University of Massachusetts