Determinants of suboptimal CD4+ T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV‐1 infection

Abstract

Up to 30% of individuals treated with antiretroviral therapy (ART) during chronic HIV fail to recover CD4 counts to >500 cells/mm3 despite plasma viral suppression. We investigated the frequency and associations of suboptimal CD4 recovery after ART started during acute HIV infection (AHI).

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 01, 2020
Source ID
10.1002/jia2.25585

Entities

People

  • Carlo Sacdalan
  • Chutharat Munkong
  • Donn Colby
  • Eugène Kroon
  • Irini Sereti
  • Jennifer Chiarella
  • Jintanat Ananworanich
  • Mark de Souza
  • Nelson Michael
  • Nittaya Phanuphak
  • Peeriya Prueksakaew
  • Robert Paul
  • Ryan Handoko
  • Sasiwimol Ubolyam
  • Serena Spudich
  • Shelly Krebs
  • Siriwat Akapirat
  • Suteeraporn Pinyakorn
  • The Search 010/rv254 Study Team
  • Victor G Valcour

Organizations

  • Armed Forces Research Institute of Medical Sciences
  • Division of Intramural Research, National Institute of Allergy and Infectious Diseases
  • Gilead Sciences
  • Henry M. Jackson Foundation for the Advancement of Military Medicine
  • Merck & Co.
  • National Institute of Allergy and Infectious Diseases
  • National Institutes of Health
  • Thai Red Cross Society
  • U.S. Military HIV Research Program
  • University of California, San Francisco
  • University of Missouri–St. Louis
  • ViiV Healthcare
  • Walter Reed Army Institute of Research
  • Yale School of Medicine

Tags

Fields of Study

  • Medicine

Readers

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