Radiomic Features of Primary Rectal Cancers on Baseline T2‐Weighted MRI Are Associated With Pathologic Complete Response to Neoadjuvant Chemoradiation: A Multisite Study
Abstract
Twenty‐five percent of rectal adenocarcinoma patients achieve pathologic complete response (pCR) to neoadjuvant chemoradiation and could avoid proctectomy. However, pretreatment clinical or imaging markers are lacking in predicting response to chemoradiation. Radiomic texture features from MRI have recently been associated with therapeutic response in other cancers.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 26, 2020
- Source ID
- 10.1002/jmri.27140
Entities
People
- Anant Madabhushi
- Andrei Purysko
- Asya Ofshteyn
- Eric L. Marderstein
- Erik Y. Wang
- Jacob Antunes
- Jayakrishna Gollamudi
- Joseph E. Willis
- Justin T. Brady
- Kaustav Bera
- Kenneth A. Friedman
- Matthew F. Kalady
- Rajmohan Paspulati
- Satish E Viswanath
- Sharon L. Stein
Organizations
- Case Western Reserve University
- Cleveland Clinic
- National Cancer Institute
- National Center for Research Resources
- National Institute of Biomedical Imaging and Bioengineering
- UH Cleveland Medical Center
- United States Department of Defense
- Veterans Health Administration
- Wallace H. Coulter Foundation