A randomized double‐blind clinical trial evaluating comparative plaque and gingival health associated with commercially available stannous fluoride‐containing dentifrices as compared to a sodium fluoride control dentifrice

Abstract

Gingivitis is a non‐specific inflammatory lesion in response to the accumulation of oral biofilm and is a necessary precursor to periodontitis. Enhanced oral hygiene practices, including utilization of a dentifrice that could significantly improve plaque accumulation and gingival inflammation, is desirable to prevent and treat gingivitis and potentially prevent progression to periodontitis. This clinical study aimed to investigate the effect of a new stannous fluoride‐containing dentifrice with 2.6% ethylenediamine tetra acetic acid (EDTA) as an anti‐tartar agent to reduce plaque index and gingival index over a 3‐month study period compared to other commercially‐available fluoride‐containing dentifrices.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 26, 2023
Source ID
10.1002/jper.22-0675

Entities

People

  • Brian Novy
  • Charles M. Cobb
  • Joan Otomo‐corgel
  • Maria L. Geisinger
  • Nicolaas C. Geurs
  • Peter L. Jacobsen
  • Petra Wilder‐smith
  • Thair Takesh

Organizations

  • Air Force Office of Scientific Research
  • Arnold and Mabel Beckman Foundation
  • Harvard University
  • University of Alabama
  • University of California
  • University of Missouri
  • University of the Pacific

Tags

Fields of Study

  • Medicine

Readers

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Technology Areas

  • Biotechnology