Combat‐Related Posttraumatic Stress Disorder and Comorbid Major Depression in U.S. Veterans: The Role of Deployment Cycle Adversity and Social Support
Abstract
Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) commonly co‐occur in combat veterans, and this comorbidity has been associated with higher levels of distress and more social and economic costs compared to one disorder alone. In a secondary analysis of a multisite randomized controlled trial of a sample of veterans with combat‐related PTSD, we examined the associations among pre‐, peri‐, and postdeployment adversity, social support, and clinician‐diagnosed comorbid MDD. Participants completed the Deployment Risk and Resilience Inventory and the Beck Depression Inventory–II as well as structured clinical interviews for diagnostic status. Among 223 U.S. veterans of the military operations in Iraq and Afghanistan (86.9% male) with primary combat‐related PTSD, 69.5% had current comorbid MDD. After adjustment for sex, a linear regression model indicated that more concerns about family disruptions during deployment, f2 = 0.065; more harassment during deployment, f2 = 0.020; and lower ratings of postdeployment social support, f2 = 0.154, were associated with more severe self‐reported depression symptoms. Interventions that enhance social support as well as societal efforts to foster successful postdeployment reintegration are critical for reducing the mental health burden associated with this highly prevalent comorbidity in veterans with combat‐related PTSD.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 26, 2020
- Source ID
- 10.1002/jts.22496
Entities
People
- Amanda Khan
- Elizabeth M. Goetter
- Kimberly M. Avallone
- Margaret R. Venners
- Meredith E. Charney
- Naomi M. Simon
- Sarah Wieman
- Sheila A M Rauch
- Susanne S. Hoeppner
Organizations
- Emory University
- Harvard Medical School
- Massachusetts General Hospital
- National Science Foundation
- New York University
- Suffolk University
- United States Department of Defense
- University of Michigan
- Veterans Health Administration