Neuroprotectin D1 Attenuates Blast Overpressure Induced Reactive Microglial Cells in the Cochlea
Abstract
We examined a neuroinflammatory response associated with glial activation in the cochlea exposed to blast overpressure and evaluated the potential therapeutic efficacy of specialized pro‐resolving mediators such as neuroprotectin D1, NPD1; (10R, 17S‐dihydroxy‐4Z, 7Z, 11E, 13E, 15Z, 19Z‐docosahexaenoic acid) in a rodent blast‐induced auditory injury model.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 11, 2021
- Source ID
- 10.1002/lary.29337
Entities
People
- Carlos Esquivel
- Charles N Serhan
- Charlotte K. Hughes
- Erik K. Weitzel
- John Lally
- José David Ríos
- Nathan Wienandt
Organizations
- Harvard Medical School
- Oak Ridge Institute for Science and Education
- United States Army Institute of Surgical Research
- United States Army Medical Research and Development Command
- United States Department of Defense