The effects of laser irradiation of cartilage on chondrocyte gene expression and the collagen matrix
Abstract
Laser reshaping of cartilage is an emerging technology aimed at replacing conventional techniques for aesthetic and reconstructive surgery. Little is known about the mechanisms of wound healing following the photothermal heating during laser reshaping and, ultimately, how collagen remodels in the irradiated tissue. Healthy hyaline and elastic cartilage as found in the ear, nose, larynx, and trachea does not express collagen type I which is characteristic of fibro‐cartilage and scar tissue. The aim of the study was to determine if collagen I and II gene expression occurs within laser irradiated rabbit septal cartilage.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 28, 2009
- Source ID
- 10.1002/lsm.20795
Entities
People
- Brian J.f. Wong
- Chao Li
- Chung‐ho Sun
- David M. Gardiner
- Paul K. Holden
- Susan V. Bryant
- Victor Da Costa
Organizations
- Air Force Office of Scientific Research
- National Institutes of Health